منابع مشابه
Fold me or leave me
he only confirmed mechanism for protein-mediated membrane fusion involves the formation of helix bundles, in which helices attached to two membranes pack against one another to draw together the membranes. In the final fused state, six-helix bundles are formed by HIV Env and paramyxovirus F proteins, members of the class I group of viral fusion proteins. Although the class I founding member, in...
متن کاملFold or hold: experimental evolution in vitro
We introduce a system for experimental evolution consisting of populations of short oligonucleotides (Oli populations) evolving in a modified quantitative polymerase chain reaction (qPCR). It is tractable at the genetic, genomic, phenotypic and fitness levels. The Oli system uses DNA hairpins designed to form structures that self-prime under defined conditions. Selection acts on the phenotype o...
متن کاملShe loves me--she loves me not.
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متن کاملHe Loves Me Not.
Sir In the article in your current issue on making so-called ‘orphan drugs’ available via the NHS, it seems to be tacitly assumed that our overriding duty as physicians and surgeons is to prolong the existence of our patients whether or not that is their main preoccupation and what our overpopulated world needs. We do not of course ever ‘save’ lives when we prolong them unless we concern oursel...
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ژورنال
عنوان ژورنال: The Plant Cell
سال: 2020
ISSN: 1040-4651,1532-298X
DOI: 10.1105/tpc.20.00881